Liverpool have not lost at Selhurst Park since November 2014, when Dwight Gayle scored the opener in a 3-1 victory for a team managed by Neil Warnock. However, after seeing their title challenge falter last season following a loss at Anfield to a goal from Eberechi Eze, Arne Slot will be cautious of facing a Crystal Palace side yet to secure a win in the Premier League this season. Fresh from his stunning goal against Bologna in the Champions League, Mohamed Salah will be eager to exploit a new-look Palace defense that has struggled this season, despite a recent 0-0 draw against Manchester United. The Egyptian forward scored his 200th Liverpool goal against Palace in December, bringing his tally to eight in just 11 appearances, along with seven assists.

Kai Havertz expressed his desire to win the Champions League with Arsenal, stating, “It’s a nice feeling, but it would mean even more with Arsenal.” After his goal against Paris Saint-Germain set up a comfortable win, Havertz has a chance to match Robin van Persie’s record of scoring in seven consecutive games at the Emirates Stadium when Arsenal face Southampton. His partnership with Leandro Trossard has compensated for the absence of Martin Ødegaard, showcasing Arsenal’s adaptability during a challenging series of fixtures.

Wolves’ season has been a mixed bag, with Gary O’Neil’s team often playing well despite results. Even in the 6-2 loss to Chelsea, Wolves were level at 2-2 at halftime, playing more dangerously. However, individual mistakes cost them, a pattern repeated against Liverpool. O’Neil’s reputation was built on saving teams from relegation, but he now seeks to refine his approach. Wolves’ defensive errors have been frequent, raising questions about their strategy against Brentford.

Leicester’s defensive woes continued as they allowed 36 shots on goal against Arsenal. Despite nearly clinching a point, Steve Cooper’s winless side must improve. Mads Hermansen admitted, “No matter who you play, 36 shots is too much.” As they face Bournemouth, Leicester must tighten up, especially with Antoine Semenyo in form.

Pep Guardiola has experimented with Nico O’Reilly and double pivots to fill the Rodri void. For Fulham’s visit, Guardiola may turn to John Stones, who declared himself “100% ready.” Phil Foden’s performance in the 4-0 win over Slovan Bratislava showed both rustiness and class, ensuring no loss of quality in the absence of Kevin De Bruyne.

A fourth consecutive home defeat could spell trouble for Julen Lopetegui’s West Ham. Ipswich, seeking their first win since promotion, face an exciting yet porous team. Rumors of a dispute between Lopetegui and Mohammed Kudus have circulated, but Lopetegui’s defensive adjustments have shown promise.

Anthony Gordon’s return to Goodison Park will be under scrutiny. His performance in Newcastle’s draw with Manchester City showcased Eddie Howe’s improvements. With Alexander Isak doubtful, Gordon may again play as a center-forward against his former club.

Manchester United’s recent struggles have sparked internet outrage. Facing Unai Emery, who has beaten them with three different clubs, United must improve. Emery’s Villarreal denied Ole Gunnar Solskjær in the 2021 Europa League final, and his Villa side has since lost to United.

Chelsea, under Todd Boehly’s management, are becoming a must-watch side. The all-English attacking trio of Cole Palmer, Jadon Sancho, and Noni Madueke is flourishing, contributing nine goals and seven assists this season.

Brighton’s defensive issues were compounded by the news that Jan Paul van Hecke faces an extended absence. Fabian Hürzeler must decide whether to stick with Adam Webster or turn to Igor to partner Lewis Dunk against Tottenham.